Miami, FL | Annapolis, MD | Edgewater, MD
Roger Dherlin lives in Miami, Florida, but has also spent time in Annapolis, Maryland and Edgewater, Maryland. Some of Roger family members are George S Dherlin, Georges S Dherlin and Natalie Dherlin.
George Dherlin lives in Annapolis, Maryland. has also lived in Bethesda, Maryland. George works for Intercoastal. Roger Dherlin and Georges S Dherlin are in George family.
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Derlin-1 also known as degradation in endoplasmic reticulum protein 1 is a membrane protein that in humans is encoded by the DERL1 gene. Derlin-1 is located in the membrane of the endoplasmic reticulum (ER) and is involved in retrotranslocation of specific misfolded proteins and in ER stress. Derlin-1 is widely expressed in thyroid, fat, bone marrow and many other tissues. The protein belongs to the Derlin-family proteins consisting of derlin-1, derlin-2 and derlin-3 that are components in the endoplasmic reticulum-associated protein degradation (ERAD) pathway. The derlins mediate degradation of misfolded lumenal proteins within ER, and are named ‘der’ for their ‘Degradation in the ER’. Derlin-1 is a mammalian homologue of the yeast DER1 protein, a protein involved in the yeast ERAD pathway. Moreover, derlin-1 is a member of the rhomboid-like clan of polytopic membrane proteins.. You can find more here.
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